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In 1989 David Hood found chronic (30+ days) 10 Hz stimulation TRIPLED two critical enzymes in final stages of cell respiration, citrate synthase and cytochrome c oxidase..
Testing systemic oxygen consumption via static (resting) breath-hold-test since 2005 we have found routine improvements in as little as 2-3 days. Cell's burn oxygen so much more efficiently, drawing oxygen from blood slower, producing more energy with less oxidative waste from every breath; thus you are able to hold your breath up to 20% longer the first week or two; 2/3rds longer after a year or two and up to 100% longer after several years (though many increase their breath hold 100% during 90 day trial period). Sleep on Command™ inventor's (11+years nightly use) breath hold peaked at 2:46 after 5 years (baseline 1:20) and he smokes hand-roll cigarettes; only takes the test once every 18 months so practice is not a factor. Gets very little aerobic exercise.
In 2003 NASA-Goodwin found 10 Hz square wave stimulation caused neural tissue regeneration @ 4x baseline, w/better 3-D orientation; cell DNA signature reverted from maturation to developmental (more than 175 maturation genes switched -OFF- and 150 developmental genes switched -ON- by 21 days stimulation pgs. 15-18). You CAN'T get that effect in short sessions regardless of the frequency setting.
We discovered in 2001 that regular nighttime use of the EarthPulse™ DC pulsed electromagnetic fields at 9.6 Hz reliably enhanced mental and physical performance while providing strength and stamina gains rivaling steroids. Strength and stamina gains are equally explainable by the moreATP theory. So are upregulation of hormone levels. See our longevity experiment Gizmo the 17 year old Yorkie-Maltese and our 50 y.o. Chief after 9 years of continuous nighttime use.
NASA didn't dig into the cell physiology deep enough to adequately explain why cell regeneration QUADRUPLED under 10 Hz pulsed electromagnetic field (PEMF) or why the genetic effects occurred particularly at the single frequency of 10 Hz pulsed electromagnetic field (and not at 5 Hz or 15 Hz which was 'sanitized' out of the original version of the paper). The moreATP theory explains this effect well based upon the work of David Hood (above...who's been subjecting mitochondria at 10 Hz stimulation for decades) and Tong immediately below.
In 2007 James Tong TRIPLED nerve synapse energy & DOUBLED mitochondrial density at nerve synapses. Full text study here.
Compare DENSITY of unstimulated mitochondria (white circles) w/ 10 Hz stimulated (black circles); compare TOTAL ENERGY at synapse junction unstimulated (white circles) w/ 10 Hz stimulated (black circles) in lower chart. Density change = +2x / Energy change = +3x.
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In NASA study above, mitochondrial robustness due to 10 Hz stimulation provided the energy to support regeneration at 4 times baseline. Originally, before being 'sanitized' the paper showed 5 Hz and 15 Hz doubling cell regeneration while 10 Hz quadrupling it; unfortunately they edited the study playing 'hide the ball'.
Cells that are mature are literally "tricked" into believing they are younger than they are. Mitochondrial DNA (mtDNA) may have been repaired through same energy mechanism solely or due to adequate and detoxification of mitochondrion cell protoplasm within which the mitochondria reside, due to combination of reduced oxidative electron production and improved detoxification working synergistically.
The pulsed electromagnetic field therapy bibliographies offered below contain several hundred peer reviewed pulsed electromagnetic therapy study abstracts spanning 5 decades, organized by disorder, most linked directly to the U.S. National Institutes of Health - National Libraries of Medicine. You will notice many, if not most of these pulsed electromagnetic therapy studies use frequencies under 20 Hz.
Heretofore, evidence offered in support of various biological effects of pulsed electromagnetic fields (PEMF) has differed widely. This new theoretical proposition, MoreATP cohesively explains very simply why pulsed electromagnetic therapy at 10 Hz (+ / - 5 Hz) works as well as it does.
Nearly 6 decades of pulsed electromagnetic research indicate that a pulsed electromagnetic field (PEMF) of proper frequency intensity and duration provides beneficial effects in wide variety of cellular processes and mechanisms. But till now there was not a cohesive way to explain the effects of PEMF.
Alternative Cellular Energy (ACE) pathways for lack of better term, vaguely explained biological effects of pulsed electromagnetic fields on calcium/potassium exchange, capillary dilation, increased cell membrane potential, accelerated anti- inflammatory processes, bone formation and kind. Vaguely explained at best and holding back FDA approval of all uses. We heal bone fractures in 1/3 the time (66% less time) yet FDA won't approve PEMF treatment of fresh fractures and would rather see you in cast for 6-8 weeks because those seeking approval can't satisfactorily explain why PEMF speeds healing. Don't look a gift-horse in the mouth.
ACE pathways theory relies upon some inorganic transfer of energy to the cell. In the case of PEMF, the magnetic signal passing through the tissue is responsible for increasing cell membrane potential providing the beneficial effects. For frequencies above 20 Hz (even those pulsed electromagnetic field therapies utilizing radiofrequency) this is still the most plausible explanation as they actually debilitate mitochondrial performance.
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